Posts

Breaking down proteins: How starving cancer cells switch food sources

Image
 Breaking down proteins: How starving cancer cells switch food sources Cancer cells often grow in environments that are low in nutrients, and they cope with this challenge by switching their metabolism to using proteins as alternative "food". Building on genetic screens, an international team of scientists could identify the protein LYSET as part of a pathway that allows cancer cells to make this switch. Their findings are now published in the journal Science. Amino acids are the building blocks of proteins and key nutrients for cell growth and proliferation. Understanding how cells utilize amino acids in different environments is a central question in basic biology and cancer research. Tumor tissues often have a limited blood supply, and to grow under such conditions, cancer cells switch their metabolic activities. In particular, they switch from taking up nutrients delivered by blood vessels to exploiting alternative nutrients, such as breaking down surrounding proteins as

Hip fractures will nearly double worldwide by 2050

Image
 Hip fractures will nearly double worldwide by 2050 Osteoporotic hip fracture, already a dangerous and debilitating problem for older men and women worldwide, is poised to become a far more severe global public-health issue as the population grows older and frailer, according to a new study led by researchers at the University of Hong Kong. The risk—and thus the need for far better study, prevention and treatment of osteoporosis and fractures—is especially great among men and those over 85 years old, the study reported. Ching-lung Cheung, Associate Professor, in the University of Hong Kong's Department of Pharmacology and Pharmacy, presented the findings today at the annual meeting of the American Society of Bone and Mineral Research in Austin, Texas. The study analyzed data in 19 countries for patients 50 and older who had fractured their hips between 2005 and 2018. It found that total hip fracture counts were expected to increase over time in 18 of the 19 countries. Hip fracture

11 Cancer symptoms you shouldn’t ignore – according to the NHS

Image
11 Cancer symptoms you shouldn’t ignore – according to the NHS Finding cancer early means it’s easier to treat. So, it’s important to be aware of any new or worrying symptoms. Speak to a GP if you notice these 11 signs and symptoms, advises the NHS. According to the healthcare provider, it’s particularly important to look out for cancer symptoms if you have been diagnosed with a condition that means you’re at higher risk of getting cancer and two or more of your close relatives (such as a parent, brother or sister) have had cancer. Coughing, chest pain and breathlessness Speak to a GP if you’ve had a cough for three weeks or more. Symptoms such as shortness of breath or chest pain may also be a sign of a condition such as pneumonia. Speak to a GP straight away if you have these types of symptoms. Changes in bowel habits Speak to a GP if you’ve noticed these changes and it’s lasted for three weeks or more: tummy discomfort, blood in your poo, diarrhoea or constipation for no obvious rea

St. Louis research fuels COVID-19 nasal vaccine rollout in India

Image
 St. Louis research fuels COVID-19 nasal vaccine rollout in India ST. LOUIS — The science behind India’s new nasal vaccine for COVID-19 has its roots in St. Louis. India-based drug company Bharat Biotech announced Tuesday that its nasal vaccine had received emergency approval. The vaccine technology was licensed from Washington University. Dr. Michael Diamond, a Washington University professor and viral immunologist, said he began working on the vaccine in the spring of 2020 with fellow Washington University professor Dr. David Curiel. The world’s scientific community was just mobilizing on its massive, urgent search for methods to treat and prevent the new coronavirus. Diamond and Curiel knew many other researchers were racing to develop vaccines, but they didn’t see anyone else pursuing oral or nasal vaccines. Their work is now making its public debut nearly two years after the injectable products made by Pfizer, Moderna and others. But it could become a strong tool in the fight agai

Molecular makeover makes wimpy antibody a SARS-CoV-2 tackler

 Molecular makeover makes wimpy antibody a SARS-CoV-2 tackler Like the Roadrunner outwitting Wile E. Coyote, SARS-CoV-2 (the infectious virus responsible for COVID-19) keeps mutating, generating new variants that can slip from the grip of a well-trained immune system or a well-aimed drug or vaccine. Now, Stanford Medicine scientists have found a way to imbue immune molecules once thought useless with the ability to put SARS-CoV-2 in a therapeutic headlock it can't wriggle out of. Their method is described in a paper published Sept. 8 in Nature Chemical Biology. The study was led by biologist and vaccinologist Peter Kim, Ph.D. Two things about the study stand out. First, although it's not ready yet for use in humans, it's a solid step toward the development of broadly effective drugs that don't stop working just because a nasty virus has thought up a new trick. And second, a key component of the new therapy was a molecule that had been routinely getting tossed in the tra

Internet Computer Price Prediction I in-depth Analysis and technical overview ICP to USD, Get free forecast for 2022,2023, 2024,2025, to 2030

Image
      Internet Computer Price Prediction I in-depth Analysis and technical overview ICP to USD, Get free forecast for 2022,2023, 2024,2025, to 2030  Internet Computer Price Prediction  The blockchain business continues developing, with new activities springing up constantly. Yet, a couple of them are drawing in truly strong fascination from the blockchain local area. This article will zero in on one such undertaking: The Internet Computer (ICP). You might have proactively seen the rise of this new cryptographic money, which immediately became one of the biggest regarding market capitalization. In this article, we’ll investigate The Internet Computer project, lead a specialized examination of the ICP coin, and look at specialists’ cost forecasts. Internet Computer Price Prediction Web Computer as of now remains at $5.97 USD with a market capitalization of $1,443,691,198, making it rank 37 on the most significant coins list. ICP has a 24-hour volume of $69,802,628, as indicated by TechNe

Swedish Vs Deep Tissue Massage

Image
    Swedish Vs Deep Tissue Massage Swedish vs deep tissue massage are both well-known kinds of massage treatments. While there are a few likenesses, they are not the same as one another. The distinctions are: The strain Procedure Expected use Areas of concentration Swedish massage utilizes long strokes and light-to-firm strain to give delicate unwinding. Deep tissue massage is a more strong strategy that discharges pressure somewhere down in the muscles and connective tissues. Swedish vs deep tissue hopkinrx Swedish massage includes long, floating strokes in blend with manipulating and contact to deliver surface strain. Swedish massage utilizes five essential strokes, which structure the premise of numerous different sorts of massage treatment. The five fundamental strokes are: Effleurage: This massage development includes long, delicate, cadenced strokes across the skin. Other than being profoundly unwinding, these strokes permit the massage advisor to feel the general muscle tone and